Author: Moody, M. Anthony
Title: Modulation of HIV-1 immunity by adjuvants Document date: 2014_4_10
ID: 1nm1tbig_1
Snippet: Many hurdles remain for the development of a globally deployable HIV-1 vaccine. Elicitation of a durable immune response that can prevent HIV-1 infection or disease will likely require the use of an adjuvant for some or all immunizations. At present in the USA there are only two licensed adjuvants, although other adjuvanted vaccines are licensed in other parts of the world, and many more have been tested in human and animal trials. This review wi.....
Document: Many hurdles remain for the development of a globally deployable HIV-1 vaccine. Elicitation of a durable immune response that can prevent HIV-1 infection or disease will likely require the use of an adjuvant for some or all immunizations. At present in the USA there are only two licensed adjuvants, although other adjuvanted vaccines are licensed in other parts of the world, and many more have been tested in human and animal trials. This review will highlight recent work in adjuvant development for HIV-1 vaccines with particular emphasis on antibody responses.
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