Selected article for: "resistant strain and susceptible strain"
Author: Muhammad, Azharuddin; Toufeeq, Shahzad; Yu, Hai-Zhong; Wang, Jie; Zhang, Shang-Zhi; Li, Bing; Li, Zhen; Yang, Li-Ang; Hu, Pei; Ma, Yan; Xu, Jia-Ping
Title: Molecular Characterization of Two Mitogen-Activated Protein Kinases: p38 MAP Kinase and Ribosomal S6 Kinase From Bombyx mori (Lepidoptera: Bombycidae), and Insight Into Their Roles in Response to BmNPV Infection
  • Document date: 2019_2_2
    • ID: 2s3x6sj8_43
    Snippet: expression in different silkworm strains showed that Bmp38 expression was upregulated in BC9 (resistant strain) than P50 (susceptible strain). The translation data confirmed that Bmp38 expression was higher in the BC9 than in the P50. We also observed the expression of Bmp38 in the midgut post-BmNPV infection. The results showed that Bmp38 expression was upregulated in P50+ and BC9+ than control. Moreover, expression in the BC9 was higher than P5.....
    Document: expression in different silkworm strains showed that Bmp38 expression was upregulated in BC9 (resistant strain) than P50 (susceptible strain). The translation data confirmed that Bmp38 expression was higher in the BC9 than in the P50. We also observed the expression of Bmp38 in the midgut post-BmNPV infection. The results showed that Bmp38 expression was upregulated in P50+ and BC9+ than control. Moreover, expression in the BC9 was higher than P50 after BmNPV infection. Immunoblot results confirmed that Bmp38 expression was higher in the BC9 than in the P50. These findings are in accordance with our previous iTRAQ database (Yu et al. 2017b) . Similar evidence from different organisms showed p38 MAPK signaling pathway mRNA expression was increased after pathogen infection (He et al. , 2018 Yan et al. 2013; Zhu et al. 2014) . A p38 protein from Scylla paramamosain showed that it is involved in immune response against bacteria and virus (Yu et al. 2017c ). These findings suggest that Bmp38 may be involved in immune response against BmNPV.

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