Author: Daniels, Keith A.; Devora, Gene; Lai, Wayne C.; O'Donnell, Carey L.; Bennett, Michael; Welsh, Raymond M.
Title: Murine Cytomegalovirus Is Regulated by a Discrete Subset of Natural Killer Cells Reactive with Monoclonal Antibody to Ly49h Document date: 2001_7_2
ID: 6n3dmle6_30
Snippet: In an additional control experiment, mAb 1F8 inoculation into irradiated (C57BL/6 Ï« DBA/2) F1 hybrid host mice did not inhibit their ability to reject C57BL/6 bone marrow cell grafts, even though there was a loss in host NK cells expressing Ly49 C, I, and H (unpublished observations). This means that many NK cell functions remain intact in mice depleted of NK cell subsets with this mAb......
Document: In an additional control experiment, mAb 1F8 inoculation into irradiated (C57BL/6 Ï« DBA/2) F1 hybrid host mice did not inhibit their ability to reject C57BL/6 bone marrow cell grafts, even though there was a loss in host NK cells expressing Ly49 C, I, and H (unpublished observations). This means that many NK cell functions remain intact in mice depleted of NK cell subsets with this mAb.
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