Plasma citrulline, arginine, nitric oxide, and blood ammonia levels in neonatal calves with acute diarrhea

Gultekin, Mehmet; Voyvoda, Huseyin; Ural, Kerem; Erdogan, Hasan; Balikci, Canberk; Gultekin, Gamze

Plasma NO and blood ammonia concentrations were significantly higher in the infectious diarrhea subgroups than in the control group ( Figure 1C,D) . Plasma NO concentration was higher in severe diarrhea (FS 3) subgroup ( Figure 2C ) whereas blood ammonia concentration was higher in both moderate (P < .01) and severe diarrhea (P < .001) subgroups ( Figure 2D ). Both variables were also significantly higher in the severe dehydrated diarrheic subgroup than in the healthy control group ( Figure 3C,D) , as well as the mild (P < .001) and moderate dehy- The relationships between plasma CIT and its related variables and independent variables (age, diarrhea etiology, SIRS status) by linear regression in diarrheic calves are presented in Table 3 . There was no significant effect of age on plasma log-transformed CIT, ARG, and NO as well as blood ammonia concentrations. By contrast, the pres- Furthermore, diarrhea etiology was found to be positively associated with plasma log-transformed NO and blood ammonia (Table 3 ).