Author: Poltronieri, Palmiro; Sun, Binlian; Mallardo, Massimo
Title: RNA Viruses: RNA Roles in Pathogenesis, Coreplication and Viral Load Document date: 2015_10_23
ID: 259cspey_13
Snippet: Recent computational studies confirm the association between L1 expression and the generation of small RNAs. L1 expression seems to have a role in the activation of small RNA expression as emerged comparing data from L1-active and L1-silenced breast cancer cells. Cells in which L1 expression was silenced greatly increased the expression of a number of miRNAs, in particular members of the let-7 family, few piwiRNAs and several repeat-RNAs targetin.....
Document: Recent computational studies confirm the association between L1 expression and the generation of small RNAs. L1 expression seems to have a role in the activation of small RNA expression as emerged comparing data from L1-active and L1-silenced breast cancer cells. Cells in which L1 expression was silenced greatly increased the expression of a number of miRNAs, in particular members of the let-7 family, few piwiRNAs and several repeat-RNAs targeting LTRs, LINEs and SINE elements [9] .
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