Clinical Features and Radiological Findings of Adenovirus Pneumonia Associated with Progression to Acute Respiratory Distress Syndrome: A Single Center Study in 19 Adult Patients

Cha, Min Jae; Chung, Myung Jin; Lee, Kyung Soo; Kim, Tae Jung; Kim, Tae Sung; Chong, Semin; Han, Jungho

He visited our hospital on 10th day from onset of his symptoms, which were abruptly aggravated two days prior. A. Chest radiograph demonstrates multifocal or diffuse opacity. B. Chest CT scan obtained on same day demonstrates extensive airspace lesions in both lungs, with bilateral pleural effusions. Total CT score was 13. Culture of BAL fluid helped confirm adenovirus pneumonia. On next day, patient was transferred to intensive care unit, and he eventually expired on 21st day of hospitalization. BAL = bronchoalveolar lavage, CT = computed tomography Korean J Radiol 17(6), Nov/Dec 2016 kjronline.org conditions (p = 0.650). Regarding the radiological findings, there was no significant difference in initial radiograph findings (p = 0.813), but the radiographic pattern of disease course differed significantly between the ARDS and non-ARDS groups (p = 0.048). In the non-ARDS group, types 1 and 2 accounted for more than 85% of patients, and no one was classified as type 4. In contrast, half of the patients in the ARDS group showed progressive deterioration of chest radiographs and were classified as type 4. Among the CT findings, the presence of pleural effusion and total CT scores differed significantly (p = 0.010 and p = 0.007, respectively) between the two groups. Patients who progressed to ARDS showed higher total CT scores and a higher probability of pleural effusion. Other CT features, such as laterality (p = 0.998), presence of consolidation (p = 0.305) and micronodules (p = 0.997), inter-or