Author: Hayward, Gail; Thompson, Matthew; Heneghan, Carl; Perera, Rafael; Del Mar, Chris; Glasziou, Paul
Title: Corticosteroids for pain relief in sore throat: systematic review and meta-analysis Document date: 2009_8_6
ID: 67bhdlzy_12
Snippet: We expressed dichotomous outcomes as relative risks and 95% confidence intervals and expressed continuous variables as weighted mean difference and 95% confidence intervals. If data were sufficient for primary outcomes, we calculated the number needed to treat using the relative risk and the pooled event rates, in addition to the risk difference as calculated in RevMan 4.2. We used the I2 statistic to measure the proportion of statistical heterog.....
Document: We expressed dichotomous outcomes as relative risks and 95% confidence intervals and expressed continuous variables as weighted mean difference and 95% confidence intervals. If data were sufficient for primary outcomes, we calculated the number needed to treat using the relative risk and the pooled event rates, in addition to the risk difference as calculated in RevMan 4.2. We used the I2 statistic to measure the proportion of statistical heterogeneity for each outcome.20 Where no heterogeneity was present, we undertook a fixed effect meta-analysis. If substantial heterogeneity (I2 above 50%) was detected, we looked for the direction of effect and where applicable used a random effects analysis. We also performed a sensitivity analysis by removing single trials to investigate the extent to which they contributed to the heterogeneity, particularly looking at baseline characteristics including severity.
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