Author: Shereen, Muhammad Adnan; Khan, Suliman; Kazmi, Abeer; Bashir, Nadia; Siddique, Rabeea
Title: COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses Document date: 2020_3_16
ID: 1mjaycee_8
Snippet: SARS-CoV-2 possesses the typical coronavirus structure with spike protein and also expressed other polyproteins, nucleopro-teins, and membrane proteins, such as RNA polymerase, 3chymotrypsin-like protease, papain-like protease, helicase, glycoprotein, and accessory proteins [30, 31] . The spike protein of SARS-CoV-2 contains a 3-D structure in the RBD region to maintain the van der Waals forces [32] . The 394 glutamine residue in the RBD region o.....
Document: SARS-CoV-2 possesses the typical coronavirus structure with spike protein and also expressed other polyproteins, nucleopro-teins, and membrane proteins, such as RNA polymerase, 3chymotrypsin-like protease, papain-like protease, helicase, glycoprotein, and accessory proteins [30, 31] . The spike protein of SARS-CoV-2 contains a 3-D structure in the RBD region to maintain the van der Waals forces [32] . The 394 glutamine residue in the RBD region of SARS-CoV-2 is recognized by the critical lysine 31 residue on the human ACE2 receptor [33] . The entire mechanism of pathogenicity of SARS-CoV-2, from attachment to replication is well mentioned in Fig. 3 .
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