Selected article for: "different hla and population coverage"
Author: Alba Grifoni; John Sidney; Yun Zhang; Richard H Scheuermann; Bjoern Peters; Alessandro Sette
Title: Candidate targets for immune responses to 2019-Novel Coronavirus (nCoV): sequence homology- and bioinformatic-based predictions
  • Document date: 2020_2_20
    • ID: 8p1agcm2_13
    Snippet: In parallel, we also sought to define likely CD8 epitopes. Here a different approach was required since the overlap between different HLA class I allelic variants and loci is more limited to specific groups of alleles, or supertypes (15) . Following a previously validated approach (16), we assembled a set of the 12 most prominent HLA class I alleles which have been shown to allow broad coverage of the general population, as described in the Metho.....
    Document: In parallel, we also sought to define likely CD8 epitopes. Here a different approach was required since the overlap between different HLA class I allelic variants and loci is more limited to specific groups of alleles, or supertypes (15) . Following a previously validated approach (16), we assembled a set of the 12 most prominent HLA class I alleles which have been shown to allow broad coverage of the general population, as described in the Methods (see also Table S5) .

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