Author: Sousa, Carole; Golebiewska, Anna; Poovathingal, Suresh K; Kaoma, Tony; Pires-Afonso, Yolanda; Martina, Silvia; Coowar, Djalil; Azuaje, Francisco; Skupin, Alexander; Balling, Rudi; Biber, Knut; Niclou, Simone P; Michelucci, Alessandro
Title: Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures Document date: 2018_9_11
ID: 0662rivp_21
Snippet: To study the effect of a single-dose peripheral injection of LPS dissolved in PBS, we considered our saline (PBS) group as our vehicle control. Differently from an intracranial injection of LPS where a non-injected control would be essential to discern between the effects of the injury from the LPS, we believe that the effect on the CNS of a single intraperitoneal puncture would be minimal or absent......
Document: To study the effect of a single-dose peripheral injection of LPS dissolved in PBS, we considered our saline (PBS) group as our vehicle control. Differently from an intracranial injection of LPS where a non-injected control would be essential to discern between the effects of the injury from the LPS, we believe that the effect on the CNS of a single intraperitoneal puncture would be minimal or absent.
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