Author: Munday, Diane C.; Emmott, Edward; Surtees, Rebecca; Lardeau, Charles-Hugues; Wu, Weining; Duprex, W. Paul; Dove, Brian K.; Barr, John N.; Hiscox, Julian A.
Title: Quantitative Proteomic Analysis of A549 Cells Infected with Human Respiratory Syncytial Virus Document date: 2010_7_20
ID: 2zhaknbi_54
Snippet: HRSV Pathologies and Immune Signaling-In this quantitative proteomic analysis, several different proteins involved in the pathologies and the immune signaling associated with HRSV infection were altered. For example, IPA highlighted proteins that were previously identified as being associated with pneumonitis, inflammation, and respiratory disease. Expansion of a quantitative proteomic analysis to in vivo tissue samples and the use of isobaric ta.....
Document: HRSV Pathologies and Immune Signaling-In this quantitative proteomic analysis, several different proteins involved in the pathologies and the immune signaling associated with HRSV infection were altered. For example, IPA highlighted proteins that were previously identified as being associated with pneumonitis, inflammation, and respiratory disease. Expansion of a quantitative proteomic analysis to in vivo tissue samples and the use of isobaric tags (e.g. iTRAQ (isobaric tags for relative and absolute quantitation)) may further the investigation of possible links between HRSV infection and diseases such as asthma.
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