Author: Tuplin, A.; Evans, D. J.; Buckley, A.; Jones, I. M.; Gould, E. A.; Gritsun, T. S.
Title: Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus Document date: 2011_5_27
ID: 0aiaklrn_28
Snippet: Structure predictions correlated with evidence for SSSV in TBFV genomes ( Figure 2) . A remarkable drop in SSSV was observed in the SL6 region between positions 209 and 254 of the Vs sequence. The most extreme drop in variability was observed in a window centred on position 221 within the apical stem of SL6. The levels of SSSV within the remainder of the structural protein-encoding region (positions 295-2435) were higher than the upstream portion.....
Document: Structure predictions correlated with evidence for SSSV in TBFV genomes ( Figure 2) . A remarkable drop in SSSV was observed in the SL6 region between positions 209 and 254 of the Vs sequence. The most extreme drop in variability was observed in a window centred on position 221 within the apical stem of SL6. The levels of SSSV within the remainder of the structural protein-encoding region (positions 295-2435) were higher than the upstream portion. Similarly, high levels of SSSV were observed across the non-structural portion of the genome between positions 322 and 2425 (data not shown).
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