Author: Poltronieri, Palmiro; Sun, Binlian; Mallardo, Massimo
Title: RNA Viruses: RNA Roles in Pathogenesis, Coreplication and Viral Load Document date: 2015_10_23
ID: 259cspey_54
Snippet: Vpr also can regulate several proteins and host factors, some of them can affect RNA replication. The most interesting are TERT [67] , the type I interferon regulatory factor 3 (IRF-3) [75] , A3G [76] , TRIM proteins [77] , uracil DNA glycosylase 2 (UNG2) [78] and single strand selective monofunctional uracil-DNA glycosylase 1 (SMUG1). A premature activation of the SLX4 complex has been shown dependent on Vpr, promoting G2/M arrest and escape fro.....
Document: Vpr also can regulate several proteins and host factors, some of them can affect RNA replication. The most interesting are TERT [67] , the type I interferon regulatory factor 3 (IRF-3) [75] , A3G [76] , TRIM proteins [77] , uracil DNA glycosylase 2 (UNG2) [78] and single strand selective monofunctional uracil-DNA glycosylase 1 (SMUG1). A premature activation of the SLX4 complex has been shown dependent on Vpr, promoting G2/M arrest and escape from innate immune sensing [79] .
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