Author: Sztuba-Solinska, Joanna; Teramoto, Tadahisa; Rausch, Jason W.; Shapiro, Bruce A.; Padmanabhan, Radhakrishnan; Le Grice, Stuart F. J.
Title: Structural complexity of Dengue virus untranslated regions: cis-acting RNA motifs and pseudoknot interactions modulating functionality of the viral genome Document date: 2013_3_26
ID: 1pbd4maf_1
Snippet: Unlike cellular mRNAs, which only contain translational regulatory motifs, viral RNA genomes have evolved functional regions, which act at different stages of their life cycle. These specific structures, their interactions and association with host proteins and ligands, together orchestrate the multifunctionality of viral RNA genomes. Often, RNA-RNA interactions spanning significant distances (1,2) bring regulatory motifs into proximity, changing.....
Document: Unlike cellular mRNAs, which only contain translational regulatory motifs, viral RNA genomes have evolved functional regions, which act at different stages of their life cycle. These specific structures, their interactions and association with host proteins and ligands, together orchestrate the multifunctionality of viral RNA genomes. Often, RNA-RNA interactions spanning significant distances (1,2) bring regulatory motifs into proximity, changing our view of a functional viral RNA genome from that of a linear molecule to one whose 3D structure is an important contributor during the life cycle (3, 4) .
Search related documents:
Co phrase search for related documents- association interaction and life cycle: 1, 2
- association interaction and RNA genome: 1
- association interaction and viral RNA genome: 1
- different stage and host protein: 1
- different stage and life cycle: 1, 2, 3, 4, 5, 6
- different stage and life cycle different stage: 1, 2, 3, 4, 5
- different stage and RNA genome: 1
- functional region and host protein: 1, 2, 3
- functional region and life cycle: 1
- functional region and RNA genome: 1
- host protein and life cycle: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73
- host protein and ligand host protein: 1, 2, 3
- host protein and RNA genome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53
- host protein and specific structure: 1, 2
- host protein and viral RNA genome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21
- important contributor and RNA genome: 1
- life cycle and RNA genome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74
- life cycle and RNA RNA interaction: 1, 2, 3, 4
- life cycle and significant distance: 1
Co phrase search for related documents, hyperlinks ordered by date