Title: Targeting of protein ERGIC-53 to the ER/ERGIC/cis-Golgi recycling pathway Document date: 1995_10_1
ID: 7oklz2ch_3
Snippet: The mannose-specific lectin ERGIC-53 (Schindler et al., zer et al., 1988 (Schindler et al., zer et al., , 1990 (Schindler et al., zer et al., , 1991 . Due to continuous recycling, ERGIC-53 and its rat homologue p58 (Saraste and Svensson, 1991) are also present at lower concentrations in the rough ER and in the first fenestrated cis-cisternae of the stacked Golgi (Foguet, M., and H.-P. Hauri, unpublished observation; Schweizer et al., 1988; Chavri.....
Document: The mannose-specific lectin ERGIC-53 (Schindler et al., zer et al., 1988 (Schindler et al., zer et al., , 1990 (Schindler et al., zer et al., , 1991 . Due to continuous recycling, ERGIC-53 and its rat homologue p58 (Saraste and Svensson, 1991) are also present at lower concentrations in the rough ER and in the first fenestrated cis-cisternae of the stacked Golgi (Foguet, M., and H.-P. Hauri, unpublished observation; Schweizer et al., 1988; Chavrier et al., 1990) . ERGIC-53 is a 53-kD nonglycosylated type I transmembrane protein that assembles into equal amounts of disulfide-linked homodimers and homohexamers (Schweizer et al., 1988; Schindler et al., 1993) . It has a large lumenal domain exhibiting homology to leguminous lectins and mammalian galectins, a single transmembrane segment, and a short 12-amino acid long cytoplasmic domain (Schindler et al., 1993; Fiedler and Simons, 1994; Arar et al., 1995) . The cytoplasmic domain contains a COOH-terminal tetrapeptide, KKFF, matching the consensus for a di-lysine ER-retrieval signal.
Search related documents:
Co phrase search for related documents- ER retrieval signal and transmembrane protein: 1
- homologue p58 and rat homologue p58: 1
- homologue p58 and transmembrane protein: 1
- long cytoplasmic domain and transmembrane protein: 1
- lumenal domain and transmembrane protein: 1, 2, 3, 4, 5, 6, 7
- lumenal domain and transmembrane segment: 1, 2, 3
- nonglycosylated type and transmembrane protein: 1
- rat homologue p58 and transmembrane protein: 1
- single transmembrane segment and transmembrane protein: 1, 2
- single transmembrane segment and transmembrane segment: 1, 2, 3, 4, 5, 6
Co phrase search for related documents, hyperlinks ordered by date