Title: 2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018 Document date: 2018_10_25
ID: 60ceejq1_6
Snippet: These effects have been demonstrated to be independent of sotalol';s ß-blocking properties. However, ß blockade may result in reduced myocardial contractility and also contribute to slowing of the sinus rate. In patients with existing heart disease, a cardiodepressant drug effect may be clinically relevant, yet the inotropic properties of sotalol are not well-characterized in dogs. The aim of this study was to investigate the inotropic and chro.....
Document: These effects have been demonstrated to be independent of sotalol';s ß-blocking properties. However, ß blockade may result in reduced myocardial contractility and also contribute to slowing of the sinus rate. In patients with existing heart disease, a cardiodepressant drug effect may be clinically relevant, yet the inotropic properties of sotalol are not well-characterized in dogs. The aim of this study was to investigate the inotropic and chronotropic effects of sotalol on healthy, awake dogs.
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