Author: George, Melissa R
Title: Hemophagocytic lymphohistiocytosis: review of etiologies and management Document date: 2014_6_12
ID: 3frxd1c1_47
Snippet: HLH is a diverse condition with many causes and is likely under-recognized, which contributes to its high morbidity and mortality. Early recognition is crucial for any reasonable attempt at curative therapy to be made. HLH-94, HLH-2004, and ATG treatment regimens followed by HSCT have greatly increased survival in this devastating disease. A number of recent studies have contributed to the understanding of HLH pathophysiology, leading to alternat.....
Document: HLH is a diverse condition with many causes and is likely under-recognized, which contributes to its high morbidity and mortality. Early recognition is crucial for any reasonable attempt at curative therapy to be made. HLH-94, HLH-2004, and ATG treatment regimens followed by HSCT have greatly increased survival in this devastating disease. A number of recent studies have contributed to the understanding of HLH pathophysiology, leading to alternate treatment options; however, much work remains to raise awareness and improve the effectiveness of treatment regimens.
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