Author: Meyer Sauteur, Patrick M; Krautter, Selina; Ambroggio, Lilliam; Seiler, Michelle; Paioni, Paolo; Relly, Christa; Capaul, Riccarda; Kellenberger, Christian; Haas, Thorsten; Gysin, Claudine; Bachmann, Lucas M; van Rossum, Annemarie M C; Berger, Christoph
Title: Improved Diagnostics Help to Identify Clinical Features and Biomarkers That Predict Mycoplasma pneumoniae Community-acquired Pneumonia in Children Document date: 2019_10_26
ID: 1xkc01l5_7
Snippet: After study closure, pharyngeal swab samples kept at −80°C were additionally tested for Streptococcus pneumoniae (Sp) by real-time PCR [15] , knowing that detection of Sp in the URT is likely colonization and not infection [16] . In fact, coinfection with Sp and Mp is uncommon, whereas co-colonization may be more common [4, 12] . Another 23 viral and bacterial respiratory pathogens were tested using the ePlex respiratory pathogen panel (GenMar.....
Document: After study closure, pharyngeal swab samples kept at −80°C were additionally tested for Streptococcus pneumoniae (Sp) by real-time PCR [15] , knowing that detection of Sp in the URT is likely colonization and not infection [16] . In fact, coinfection with Sp and Mp is uncommon, whereas co-colonization may be more common [4, 12] . Another 23 viral and bacterial respiratory pathogens were tested using the ePlex respiratory pathogen panel (GenMark Diagnostics, Carlsbad, California), as previously described [17] . In addition, Mp serology was performed (Virion\Serion, Würzburg, Germany). The study test results were not available to treating clinicians.
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