Selected article for: "intensity profile and query base"
Author: Lee, Charlie Wah Heng; Koh, Chee Wee; Chan, Yang Sun; Aw, Pauline Poh Kim; Loh, Kuan Hon; Han, Bing Ling; Thien, Pei Ling; Nai, Geraldine Yi Wen; Hibberd, Martin L.; Wong, Christopher W.; Sung, Wing-Kin
Title: Large-scale evolutionary surveillance of the 2009 H1N1 influenza A virus using resequencing arrays
  • Document date: 2010_2_25
    • ID: 1rhy8td0_18
    Snippet: EvolSTAR employs a two-step process for base-calling ( Figure 1 ). In the first step, each base query is scrutinized for signs of hybridization intensity abnormalities. If the gain-of-signal of the query base is strong and has no mutation, the base is called. In the second step, EvolSTAR then tries to recover base queries that have any hybridization intensity abnormalities with two analysis methods, namely neighbourhood hybridization intensity pr.....
    Document: EvolSTAR employs a two-step process for base-calling ( Figure 1 ). In the first step, each base query is scrutinized for signs of hybridization intensity abnormalities. If the gain-of-signal of the query base is strong and has no mutation, the base is called. In the second step, EvolSTAR then tries to recover base queries that have any hybridization intensity abnormalities with two analysis methods, namely neighbourhood hybridization intensity profile analysis and nucleotide substitution bias analysis.

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