Transmission of Respiratory Syncytial Virus Among Children Under 5 Years in Households of Rural Communities, the Philippines

Otomaru, Hirono; Kamigaki, Taro; Tamaki, Raita; Okamoto, Michiko; Alday, Portia Parian; Tan, Alvin Gue; Manalo, Joanna Ina; Segubre-Mercado, Edelwisa; Inobaya, Marianette Tawat; Tallo, Veronica; Lupisan, Socorro; Oshitani, Hitoshi

An RSV epidemic occurred in 2014 and 2015 in the study sites. In 2014, RSV-A was dominant in both municipalities, whereas in 2015, RSV-B was dominant, with more cases in Caibiran (see Supplementary Figure 2 ) [26] . Among the ARI episodes defined in a previous study [21] , we determined 506 households with 588 RSV-ARI. Among them, we excluded 97 households from the analysis as shown in the Figure 1 . We included 409 households with at least 1 RSV-ARI cases, with total 460 RSV-ARI cases. Of these 409 households, 19 households were further 588 RSV-ARI 506 households Children of RSV-ARI whose date of sampling was > 10 days after onset 37 RSV-ARI Children of RSV-ARI whose symptom lasted > 21 days 17 RSV-ARI Children whose RSV-ARI was occurred in the same subgroup and within a month from the previous episodes 14 RSV-ARI excluded, and the remaining 390 households were included in the analysis (Figure 1 ). For the analysis of households with 1 or more RSV-ARI cases, 181 households with 2 or more children <5 years old were further identified, whereas 209 households had only 1 child.