Title: Triggering through CD16 or phorbol esters enhances adhesion of NK cells to laminin via very late antigen 6 Document date: 1992_11_1
ID: 3ymo8zw0_23
Snippet: Our results also show that 10-15% of NK cells spontaneously adhere to LM and that VLA-6 mediates this adhesion . Similarly, low levels of VLA6-mediated adhesion to LM was observed in fresh memory human CD4+ T cells (10) . Enhancement of NK cell adhesiveness to LM is induced within a few minutes of stimulation with TPA or CD16 crosslinking, and it remains at the same level over a period of 30 min. This adhesion is still mediated by VLA6 as shown b.....
Document: Our results also show that 10-15% of NK cells spontaneously adhere to LM and that VLA-6 mediates this adhesion . Similarly, low levels of VLA6-mediated adhesion to LM was observed in fresh memory human CD4+ T cells (10) . Enhancement of NK cell adhesiveness to LM is induced within a few minutes of stimulation with TPA or CD16 crosslinking, and it remains at the same level over a period of 30 min. This adhesion is still mediated by VLA6 as shown by mAb blocking experiments .
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