MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape

Menachery, Vineet D.; Schäfer, Alexandra; Burnum-Johnson, Kristin E.; Mitchell, Hugh D.; Eisfeld, Amie J.; Walters, Kevin B.; Nicora, Carrie D.; Purvine, Samuel O.; Casey, Cameron P.; Monroe, Matthew E.; Weitz, Karl K.; Stratton, Kelly G.; Webb-Robertson, Bobbie-Jo M.; Gralinski, Lisa E.; Metz, Thomas O.; Smith, Richard D.; Waters, Katrina M.; Sims, Amy C.; Kawaoka, Yoshihiro; Baric, Ralph S.

Data Dissemination. Raw microarray data for these studies were deposited in publicly available databases in the National Center for Biotechnology Information Gene Expression Omnibus (GEO) database (37) and are accessible through GEO accession no. GSE33267 (https://www.ncbi.nlm.nih.gov/geo/ query/acc.cgi?acc=GSE33267). CHIP-Seq, MeDIP-Seq, and raw proteomics data have been made available on the Omics-LHV web portal (https://omicslhv.org/data/). Raw proteomics data corresponding to peptide identifications used to populate the AMT tag database are available at the PRoteomics IDEntification (PRIDE) database (https://www.ebi.ac.uk/pride/archive/) under the project "A Systems Biology Approach to Emerging Respiratory Viral Diseases" in the PRIDE Public Projects folder and corresponding to PRIDE accession nos. 19,877-19,890. The raw quantitative proteomics data can be accessed at the Pacific Northwest National Laboratory (PNNL) Biological Mass Spectrometry Data and Software Distribution Center (omics.pnl.gov/) in the Systems Virology Contract Data folder within the Browse Available Data folder. All data sets and associated metadata have been submitted to Virus Pathogen Resource (www.viprbrc.org/brc/home.spg?decorator=vipr).