Author: Alba Grifoni; John Sidney; Yun Zhang; Richard H Scheuermann; Bjoern Peters; Alessandro Sette
Title: Candidate targets for immune responses to 2019-Novel Coronavirus (nCoV): sequence homology- and bioinformatic-based predictions Document date: 2020_2_20
ID: 8p1agcm2_25
Snippet: All full-length protein sequences from SARS-CoV and MERS-CoV were retrieved from ViPR (https://www.viprbrc.org/brc/home.spg?decorator=corona) on 31 January 2020. In order to exclude sequences of experimental strains, sequences from "unknown," mouse, and monkey hosts were excluded from analysis. Remaining sequences were aligned using the MUSCLE algorithm in ViPR. Sequences causing poor alignments in a preliminary analysis were removed before compu.....
Document: All full-length protein sequences from SARS-CoV and MERS-CoV were retrieved from ViPR (https://www.viprbrc.org/brc/home.spg?decorator=corona) on 31 January 2020. In order to exclude sequences of experimental strains, sequences from "unknown," mouse, and monkey hosts were excluded from analysis. Remaining sequences were aligned using the MUSCLE algorithm in ViPR. Sequences causing poor alignments in a preliminary analysis were removed before computing the final alignment. The consensus protein sequences of each virus group were determined from the final alignments using the Sequence Variation Analysis tool in ViPR.
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