Selected article for: "disease outbreak and health organization"
Author: Hayden C. Metsky; Katherine J. Siddle; Adrianne Gladden-Young; James Qu; David K. Yang; Patrick Brehio; Andrew Goldfarb; Anne Piantadosi; Shirlee Wohl; Amber Carter; Aaron E. Lin; Kayla G. Barnes; Damien C. Tully; Björn Corleis; Scott Hennigan; Giselle Barbosa-Lima; Yasmine R. Vieira; Lauren M. Paul; Amanda L. Tan; Kimberly F. Garcia; Leda A. Parham; Ikponmwonsa Odia; Philomena Eromon; Onikepe A. Folarin; Augustine Goba; Etienne Simon-Lorière; Lisa Hensley; Angel Balmaseda; Eva Harris; Douglas Kwon; Todd M. Allen; Jonathan A. Runstadler; Sandra Smole; Fernando A. Bozza; Thiago M. L. Souza; Sharon Isern; Scott F. Michael; Ivette Lorenzana; Lee Gehrke; Irene Bosch; Gregory Ebel; Donald Grant; Christian Happi; Daniel J. Park; Andreas Gnirke; Pardis C. Sabeti; Christian B. Matranga
Title: Capturing diverse microbial sequence with comprehensive and scalable probe design
  • Document date: 2018_3_12
    • ID: a9lkhayg_27
    Snippet: To demonstrate the application of V ALL in the case of an outbreak, we applied it to samples of clinically confirmed (by qRT-PCR) Lassa fever cases from Nigeria. In 2018, Nigeria experienced a sharp increase in cases of Lassa fever, a severe hemorrhagic disease caused by LASV 45 , leading the World Health Organization and the Nigeria Centre for Disease Control to declare it an outbreak 46, 47 . Previous genome sequencing of LASV has revealed its .....
    Document: To demonstrate the application of V ALL in the case of an outbreak, we applied it to samples of clinically confirmed (by qRT-PCR) Lassa fever cases from Nigeria. In 2018, Nigeria experienced a sharp increase in cases of Lassa fever, a severe hemorrhagic disease caused by LASV 45 , leading the World Health Organization and the Nigeria Centre for Disease Control to declare it an outbreak 46, 47 . Previous genome sequencing of LASV has revealed its extensive genetic diversity, with distinct lineages circulating in different parts of the endemic region 3, 48 , and ongoing sequencing can enable rapid identification of changes in this genetic landscape.

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