Author: Yu, Xiaobo; Song, Lusheng; Petritis, Brianne; Bian, Xiaofang; Wang, Haoyu; Viloria, Jennifer; Park, Jin; Bui, Hoang; Li, Han; Wang, Jie; Liu, Lei; Yang, Liuhui; Duan, Hu; McMurray, David N.; Achkar, Jacqueline M.; Magee, Mitch; Qiu, Ji; LaBaer, Joshua
Title: Multiplexed Nucleic Acid Programmable Protein Arrays Document date: 2017_9_20
ID: 7t1o19kn_4
Snippet: Of the cell-free approaches, NAPPA has achieved the highest densities with ~ 2,300 plasmids per slide where the distance between neighboring spots is 625 µm) and the cross-talk is less than 2%. However, cross-talk is increased when the feature spacing is reduced to 375 µm [21] . With ~ 2,300 plasmids per slide, five NAPPA slides are needed to screen a proteome-scale array with over 10,000 genes [18, 30] . Therefore, an increase in spot density .....
Document: Of the cell-free approaches, NAPPA has achieved the highest densities with ~ 2,300 plasmids per slide where the distance between neighboring spots is 625 µm) and the cross-talk is less than 2%. However, cross-talk is increased when the feature spacing is reduced to 375 µm [21] . With ~ 2,300 plasmids per slide, five NAPPA slides are needed to screen a proteome-scale array with over 10,000 genes [18, 30] . Therefore, an increase in spot density would reduce the amount of labor, time, reagents, and cost needed for large-scale proteome analyses like target discovery and validation experiments.
Search related documents:
Co phrase search for related documents- cost reagent and high density: 1
- cost reagent and large scale: 1
- cross talk and high density: 1
- cross talk and large scale: 1, 2
- cross talk and NAPPA slide: 1
- feature spacing and high density: 1
- high density and large scale: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- high density and NAPPA slide: 1, 2, 3
- high density and target discovery: 1
- large scale and proteome analysis: 1, 2, 3
- large scale and proteome scale: 1, 2, 3, 4, 5, 6
- large scale and target discovery: 1, 2, 3, 4, 5
- large scale and validation experiment: 1
- proteome scale and target discovery: 1
Co phrase search for related documents, hyperlinks ordered by date