Author: Ahn, Jin Young; Sohn, Yujin; Lee, Su Hwan; Cho, Yunsuk; Hyun, Jong Hoon; Baek, Yae Jee; Jeong, Su Jin; Kim, Jung Ho; Ku, Nam Su; Yeom, Joon-Sup; Roh, Juhye; Ahn, Mi Young; Chin, Bum Sik; Kim, Young Sam; Lee, Hyukmin; Yong, Dongeun; Kim, Hyun Ok; Kim, Sinyoung; Choi, Jun Yong
Title: Use of Convalescent Plasma Therapy in Two COVID-19 Patients with Acute Respiratory Distress Syndrome in Korea Document date: 2020_4_6
ID: 1uwir5b8_20
Snippet: We could not assess neutralizing antibody titers from the convalescent plasma. Plasma with high neutralizing antibody titers is likely to be available from the patients in the convalescent phase recovered from severe infection. 20 To use plasma for treatment, a neutralization test is suggested as the optimal assay for assessing proper donor or plasma. However, some studies showed that ELISA IgG correlates well with neutralization titers in MERS c.....
Document: We could not assess neutralizing antibody titers from the convalescent plasma. Plasma with high neutralizing antibody titers is likely to be available from the patients in the convalescent phase recovered from severe infection. 20 To use plasma for treatment, a neutralization test is suggested as the optimal assay for assessing proper donor or plasma. However, some studies showed that ELISA IgG correlates well with neutralization titers in MERS cases so that it might be a suitable screening test for plasma donation. 20,21 In our cases, donors presented bilateral pneumonia in the course of COVID-19 and both showed positive results in the ELISA IgG test for SARS-CoV-2.
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