Selected article for: "BAL bronchoalveolar lavage and bronchoalveolar lavage"
Author: Xiao, Rui; Chen, Rongchang
Title: Neutrophil gelatinase-associated lipocalin as a potential novel biomarker for ventilator-associated lung injury
  • Document date: 2017_4_7
    • ID: 3e72pzui_3
    Snippet: The function of NGAL in the regulation of alveolar epithelial cells and in VALI remains to be elucidated. The expression level of NGAL, which is extensively involved in inflammation and the immune response, is an indicator of PMN activation. As an acute and secretory phase protein, NGAL is easily detected in serum and bronchoalveolar lavage (BAL) fluid (10, 11) . The aim of the present study was to demonstrate the use of NGAL as a novel diagnosti.....
    Document: The function of NGAL in the regulation of alveolar epithelial cells and in VALI remains to be elucidated. The expression level of NGAL, which is extensively involved in inflammation and the immune response, is an indicator of PMN activation. As an acute and secretory phase protein, NGAL is easily detected in serum and bronchoalveolar lavage (BAL) fluid (10, 11) . The aim of the present study was to demonstrate the use of NGAL as a novel diagnostic marker for VALI. The results indicated that NGAL levels increase in lung tissue, BAL fluid and serum during VALI in mice. Therefore, NGAL may represent a novel diagnostic marker for the early prediction of patients at high risk of VALI.

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