Author: Jartti, Laura; Langen, Henriikka; Söderlund-Venermo, Maria; Vuorinen, Tytti; Ruuskanen, Olli; Jartti, Tuomas
Title: New Respiratory Viruses and the Elderly Document date: 2011_7_6
ID: 7fwzohmu_9
Snippet: Human metapneumovirus (MPV) causes upper and lower respiratory infections in patients of all ages, but mostly in children aged less than 5 years [17] . In healthy elderly subjects, MPV-infection is rare: one large study showed MPV RNA in nasal specimens in 1-2% of symptomatic and in 0-2% of asymptomatic elderly subjects [40] . In another study, MPV was only found in 2% of patients with acute exacerbation of chronic obstructive pulmonary disease (.....
Document: Human metapneumovirus (MPV) causes upper and lower respiratory infections in patients of all ages, but mostly in children aged less than 5 years [17] . In healthy elderly subjects, MPV-infection is rare: one large study showed MPV RNA in nasal specimens in 1-2% of symptomatic and in 0-2% of asymptomatic elderly subjects [40] . In another study, MPV was only found in 2% of patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) [41] . The prevalence of symptomatic MPV infection is higher (up to 4-7%) in residents of long-term care facilities [40] . During outbreaks, up to 72% of elderly institutionalized persons may fall ill, 31% may develop radiographically confirmed pneumonia and 50% may die [42, 43] .
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