Author: Dimopoulos, G; Tsiodras, S; Lerikou, M; Chranioti, Aik; Perros, E; Anagnostopoulou, U; Karakitsos, P; Armaganidis, A
Title: Viral Profile of COPD Exacerbations According to Patients§ Document date: 2015_2_23
ID: 3rrvm787_20
Snippet: This study has some limitations. First, no quantitative PCR techniques were performed in order to test the modifications of the viral load of a specific virus which could be indicatives of the (re)activation of the virus in a previously colonized patient before the exacerbation. Second, patients with AECOPD frequently receive home care for moderate-mild episodes and for this reason we could have missed a fraction of similar episodes occurring in .....
Document: This study has some limitations. First, no quantitative PCR techniques were performed in order to test the modifications of the viral load of a specific virus which could be indicatives of the (re)activation of the virus in a previously colonized patient before the exacerbation. Second, patients with AECOPD frequently receive home care for moderate-mild episodes and for this reason we could have missed a fraction of similar episodes occurring in the community. Third, because of the low yield of sputum cultures regarding the confirmation of bacterial infections we could have missed some bacterial pathogens inhabiting or infecting the respiratory tract. Forth, there is no evident a convinced explanation for the high detection of RSV.
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