Selected article for: "brain region spatial distribution determination and specific quantification"
Author: Sousa, Carole; Golebiewska, Anna; Poovathingal, Suresh K; Kaoma, Tony; Pires-Afonso, Yolanda; Martina, Silvia; Coowar, Djalil; Azuaje, Francisco; Skupin, Alexander; Balling, Rudi; Biber, Knut; Niclou, Simone P; Michelucci, Alessandro
Title: Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures
  • Document date: 2018_9_11
    • ID: 0662rivp_90
    Snippet: The authors responded to most points raised in the review of their article submitted to EMBO Journal. However, we feel that the following points need to be addressed prior to publication in EMBO reports. 2. Determination of spatial distribution and brain region specific quantification of "subset LPS" in the CNS tissue in vivo by making use of the signature of up-and down-regulated genes as markers will add value to the study. The comparison of th.....
    Document: The authors responded to most points raised in the review of their article submitted to EMBO Journal. However, we feel that the following points need to be addressed prior to publication in EMBO reports. 2. Determination of spatial distribution and brain region specific quantification of "subset LPS" in the CNS tissue in vivo by making use of the signature of up-and down-regulated genes as markers will add value to the study. The comparison of the spatial distribution of "subset LPS" between male and female mice would add further value. This has been done.

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