Author: Fouchier, Ron A. M.
Title: Studies on Influenza Virus Transmission between Ferrets: the Public Health Risks Revisited Document date: 2015_1_23
ID: 33f94doo_8
Snippet: As a consequence of the monitoring of equipment both electronically and by visual inspection, potential exposures to virus are unlikely to go unnoticed. Upon any potential exposures, personnel receive oseltamivir treatment upon consultation with various specialists as indicated above. Such early treatment with drugs has been reported to have~80% efficacy against human influenza virus infection (20) and avian influenza virus infection (21) . Here,.....
Document: As a consequence of the monitoring of equipment both electronically and by visual inspection, potential exposures to virus are unlikely to go unnoticed. Upon any potential exposures, personnel receive oseltamivir treatment upon consultation with various specialists as indicated above. Such early treatment with drugs has been reported to have~80% efficacy against human influenza virus infection (20) and avian influenza virus infection (21) . Here, it is important to note that viruses under study in the Erasmus MC facility are evaluated for their sensitivity to oseltamivir (12) . The immediate treatment of laboratory personnel with oseltamivir upon any potential exposure to virus is thus expected to reduce the probability of LAI further, to below 0.2 ϫ (5 ϫ 10 Ϫ7 ), or Ͻ1ϫ 10 Ϫ 7 per person-year, given the average 80% efficacy in preventing laboratory-confirmed influenza.
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