Author: Andrés Pizzorno; Blandine Padey; Thomas Julien; Sophie Trouillet-Assant; Aurélien Traversier; Elisabeth Errazuriz-Cerda; Julien Fouret; Julia Dubois; Alexandre Gaymard; François-Xavier Lescure; Victoria Dulière; Pauline Brun; Samuel Constant; Julien Poissy; Bruno Lina; Yazdan Yazdanpanah; Olivier Terrier; Manuel Rosa-Calatrava
Title: Characterization and treatment of SARS-CoV-2 in nasal and bronchial human airway epithelia Document date: 2020_4_2
ID: bw9lbzvt_1
Snippet: On Dec 31, 2019, a cluster of cases of pneumonia of unknown etiology was reported in Wuhan, China. On Jan 10, 2020, a novel coronavirus, lately named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and classified into the Betacoronavirus genus, was 50 identified as the causative agent (1) . As of Mar 20, 2020, 9 days after the World Health Organization (WHO) declared the COVID-19 a pandemic (2) , the new Coronavirus disease 2019 (COV.....
Document: On Dec 31, 2019, a cluster of cases of pneumonia of unknown etiology was reported in Wuhan, China. On Jan 10, 2020, a novel coronavirus, lately named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and classified into the Betacoronavirus genus, was 50 identified as the causative agent (1) . As of Mar 20, 2020, 9 days after the World Health Organization (WHO) declared the COVID-19 a pandemic (2) , the new Coronavirus disease 2019 (COVID-19) had caused approximately 8 800 deaths among more than 210 000 confirmed cases reported mainly in China but also spreading to at least 168 other countries or territories worldwide (3). Compared to the two other coronaviruses responsible for epidemic outbreaks in the past, 55 SARS-CoV and MERS-CoV, the novel SARS-CoV-2 strain shares â“79% and â“50% genome sequence identity, respectively (4) . Not surprisingly, important differences in terms of the epidemiology and physiopathology between these three viruses have also been observed (5) (6) (7) .
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