Author: Phung, Thuy Thi Bich; Suzuki, Tadaki; Phan, Phuc Huu; Kawachi, Shoji; Furuya, Hiroyuki; Do, Huong Thu; Kageyama, Tsutomu; Ta, Tuan Anh; Dao, Nam Huu; Nunoi, Hiroyuki; Tran, Dien Minh; Le, Hai Thanh; Nakajima, Noriko
Title: Pathogen screening and prognostic factors in children with severe ARDS of pulmonary origin Document date: 2017_7_13
ID: 2k2x6jxm_28
Snippet: were higher in children with bacterial and fungal co-infections than in children with only viral infections, although, HMGB-1 levels were not | 1475 associated with a fatal outcome. The serum levels of IL-10 were associated with not only fatal outcome, but also MeV infection and AdV infection (Fig. 1B) . Therefore, IL-10 does not appear to be suitable as an independent prognostic factor of fatal outcome. The IL-6/IL-10 ratio was not associated wi.....
Document: were higher in children with bacterial and fungal co-infections than in children with only viral infections, although, HMGB-1 levels were not | 1475 associated with a fatal outcome. The serum levels of IL-10 were associated with not only fatal outcome, but also MeV infection and AdV infection (Fig. 1B) . Therefore, IL-10 does not appear to be suitable as an independent prognostic factor of fatal outcome. The IL-6/IL-10 ratio was not associated with fatal outcome. The higher IL-6/IL-10 ratio on the day of PICU admission was thought to reflect measles-specific inflammatory responses. 34 The present study had some limitations. First, our sample size was small. Second, the results, particularly the types of detected virus genomes, may have been affected by a concurrent measles outbreak.
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