Author: Harris, John P; Lopman, Ben A; Cooper, Ben S; O'Brien, Sarah J
Title: Does spatial proximity drive norovirus transmission during outbreaks in hospitals? Document date: 2013_7_12
ID: 2rvdedui_79
Snippet: A key input for constructing the transmission trees is the serial interval. Our best estimate came from the observed distribution of the difference between first and second onset dates for each outbreak, and our primary analysis made use of this empirical serial interval distribution. Often, more than one patient was ill on the first day of the outbreak, so we used the first date of illness onset in the next patient(s) for calculating the serial .....
Document: A key input for constructing the transmission trees is the serial interval. Our best estimate came from the observed distribution of the difference between first and second onset dates for each outbreak, and our primary analysis made use of this empirical serial interval distribution. Often, more than one patient was ill on the first day of the outbreak, so we used the first date of illness onset in the next patient(s) for calculating the serial interval. This gave a mean serial interval of 1.86 days (median 1 day, 95% C.I. 1.6 -2.2 days, obtained by bootstrapping).
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