Author: Zhengqiao Zhao; Bahrad A. Sokhansanj; Gail L. Rosen
Title: Characterizing geographical and temporal dynamics of novel coronavirus SARS-CoV-2 using informative subtype markers Document date: 2020_4_9
ID: 9sk11214_4
Snippet: where ISM ps,cq ptq is the relative abundance of a subtype, s, in location, c, at a date t, N s,c ptq is the total visualized in a tree format, as shown below in Figure 16 . The leaves in Figure 16 Importantly, even though the combinatorial space for potential ISMs is potentially very large due to the 197 large number of characters that may present at any one nucleotide position, only certain ISMs occur in 198 significantly large numbers in the o.....
Document: where ISM ps,cq ptq is the relative abundance of a subtype, s, in location, c, at a date t, N s,c ptq is the total visualized in a tree format, as shown below in Figure 16 . The leaves in Figure 16 Importantly, even though the combinatorial space for potential ISMs is potentially very large due to the 197 large number of characters that may present at any one nucleotide position, only certain ISMs occur in 198 significantly large numbers in the overall sequence population. Figure 3 shows the rapid decay in the 199 frequency of sequences with a given ISM, and shows that only the first nine ISMs represent subtypes that are 200
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