Author: Cordey, Samuel; Thomas, Yves; Suter, Patricia; Kaiser, Laurent
Title: Pilot Evaluation of RT-PCR/Electrospray Ionization Mass Spectrometry (PLEX-ID/Flu assay) on Influenza-Positive Specimens Document date: 2012_5_9
ID: 085v7n6k_3
Snippet: RT-PCR/electrospray ionization mass spectrometry (ESI-MS) assays were developed recently to enable the potential detection and typing of microbial agents, including influenza [9] [10] [11] [12] [13] [14] , during the same flow procedure [15] [16] [17] . This technology relies on the analysis of nucleotide base *Address correspondence to this author at the Laboratory of Virology, Division of Infectious Diseases, University of Geneva Hospitals, 4 R.....
Document: RT-PCR/electrospray ionization mass spectrometry (ESI-MS) assays were developed recently to enable the potential detection and typing of microbial agents, including influenza [9] [10] [11] [12] [13] [14] , during the same flow procedure [15] [16] [17] . This technology relies on the analysis of nucleotide base *Address correspondence to this author at the Laboratory of Virology, Division of Infectious Diseases, University of Geneva Hospitals, 4 Rue Gabrielle-Perret-Gentil, 1211 Geneva 14, Switzerland; Tel: ++41 22 3724079; Fax: ++41 22 3724097; E-mail: [email protected] composition signatures of highly variable selected regions based on the measurement of the molecular weight of PCR amplicons [12, 18] .
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