Author: Zhengqiao Zhao; Bahrad A. Sokhansanj; Gail L. Rosen
Title: Characterizing geographical and temporal dynamics of novel coronavirus SARS-CoV-2 using informative subtype markers Document date: 2020_4_9
ID: 9sk11214_10
Snippet: The majority of the remaining sites (9/16) were found in the ORF1ab polyprotein, which encodes a 229 polyprotein replicase complex that is cleaved to form nonstructural proteins that are used as RNA 230 polymerase (i.e., synthesis) machinery [16] . One site is located in the reading frame encoding the S spike 231 glycoprotein, which is responsible for viral entry and antigenicity, and thus represents an important target for 232 understanding the .....
Document: The majority of the remaining sites (9/16) were found in the ORF1ab polyprotein, which encodes a 229 polyprotein replicase complex that is cleaved to form nonstructural proteins that are used as RNA 230 polymerase (i.e., synthesis) machinery [16] . One site is located in the reading frame encoding the S spike 231 glycoprotein, which is responsible for viral entry and antigenicity, and thus represents an important target for 232 understanding the immune response, identifying antiviral therapeutics, and vaccine design [22, 34] .
Search related documents:
Co phrase search for related documents- antiviral therapeutic and important target: 1, 2, 3, 4, 5, 6
- antiviral therapeutic and nonstructural protein: 1, 2, 3, 4
- antiviral therapeutic and reading frame: 1, 2, 3
- antiviral therapeutic and vaccine design: 1, 2, 3, 4
- antiviral therapeutic and viral entry: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30
- antiviral therapeutic identify and immune response: 1
- immune response and important target: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26
- immune response and nonstructural protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39
- immune response and ORF1ab polyprotein: 1, 2, 3, 4, 5
- immune response and polyprotein replicase: 1, 2, 3, 4, 5, 6, 7
- immune response and reading frame: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35
- immune response and remain site: 1, 2
- immune response and synthesis machinery: 1, 2
- immune response and vaccine design: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74
- immune response and viral entry: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73
- important target and nonstructural protein: 1, 2, 3, 4
- important target and reading frame: 1
- important target and vaccine design: 1, 2, 3, 4, 5
- important target and viral entry: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29
Co phrase search for related documents, hyperlinks ordered by date