Author: Lee, Nak-Hyung; Lee, Jung-Ah; Park, Seung-Yong; Song, Chang-Seon; Choi, In-Soo; Lee, Joong-Bok
Title: A review of vaccine development and research for industry animals in Korea Document date: 2012_7_31
ID: 1c1jd9oz_1
Snippet: The first smallpox vaccination conducted by Edward Jenner in 1796 demonstrated that inoculation of materials collected from a lesion on a milkmaid suffering from cowpox was able to protect humans from smallpox [1] . This was a landmark moment in vaccine history since a virulent virus of one species was able to protect another species from clinical manifestations caused by a different virus that was potentially fatal. In addition, rabies vaccine w.....
Document: The first smallpox vaccination conducted by Edward Jenner in 1796 demonstrated that inoculation of materials collected from a lesion on a milkmaid suffering from cowpox was able to protect humans from smallpox [1] . This was a landmark moment in vaccine history since a virulent virus of one species was able to protect another species from clinical manifestations caused by a different virus that was potentially fatal. In addition, rabies vaccine was the very first virus deliberately attenuated in a laboratory in order to create a weakened vaccine virus for humans [2] . The next breakthrough in vaccine production came out in the 1950s when mass production of vaccine virus was achieved by adaption of in vitro preparation using chicken embryos and tissue culture cells [3, 4] .
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