Author: Ivanova, Elena; Berger, Audrey; Scherrer, Anne; Alkalaeva, Elena; Strub, Katharina
Title: Alu RNA regulates the cellular pool of active ribosomes by targeted delivery of SRP9/14 to 40S subunits Document date: 2015_3_11
ID: 64cnoqpi_28
Snippet: We further analyzed the effect of Alu RNPs on 80S complex assembly and elongation. To this end, Alu RNPs were added to the reconstituted 48S and 80S complexes before forming 80S and pre-termination complexes (preTC), respectively (('Materials and Methods' section). We observed no significant changes in the efficiencies of 80S initiation complex formation and of preTC formation in the presence of AluY A and scAluY A RNPs ( Figure 1G and H) ......
Document: We further analyzed the effect of Alu RNPs on 80S complex assembly and elongation. To this end, Alu RNPs were added to the reconstituted 48S and 80S complexes before forming 80S and pre-termination complexes (preTC), respectively (('Materials and Methods' section). We observed no significant changes in the efficiencies of 80S initiation complex formation and of preTC formation in the presence of AluY A and scAluY A RNPs ( Figure 1G and H) .
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