Author: Draz, Mohamed Shehata; Shafiee, Hadi
Title: Applications of gold nanoparticles in virus detection Document date: 2018_2_15
ID: 1xjmlwqr_47
Snippet: Flaviviridae is a large virus family comprising three main genera: Flavivirus (53 species, type species is yellow fever virus), Hepacivirus (one species, hepatitis C virus; HCV), and Pestivirus (four species, type species is bovine virus diarrhea) [127] . Flaviviruses are spherical, enveloped RNA viruses 40-65 nm in size. Their genome is nonsegmented, positive-sense ssRNA approximately 10-11 kb in size and includes one open reading frame (ORF) en.....
Document: Flaviviridae is a large virus family comprising three main genera: Flavivirus (53 species, type species is yellow fever virus), Hepacivirus (one species, hepatitis C virus; HCV), and Pestivirus (four species, type species is bovine virus diarrhea) [127] . Flaviviruses are spherical, enveloped RNA viruses 40-65 nm in size. Their genome is nonsegmented, positive-sense ssRNA approximately 10-11 kb in size and includes one open reading frame (ORF) encoding three structural proteins (C capsid; prM, premembrane; and E, envelope), and seven nonstructural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5). Several well-known human pathogens are included in this family, such as dengue virus (DENV), HCV, yellow fever virus, and West Nile virus (WNV), Japanese encephalitis virus, and Tick-borne encephalitis virus. These viruses have become increasingly serious and have been frequently involved in causing many endemics and epidemics around the world [128, 129] .
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