Title: Effect of caffeine and reduced temperature (20 degrees C) on the organization of the pre-Golgi and the Golgi stack membranes Document date: 1993_3_2
ID: 7c7slfbp_32
Snippet: Since 10 mM caffeine at 20~ did not prevent the BFA-induced retrograde movement of Golgi membranes to the ER, it was of interest to study the distribution of the pre-Golgi and the Golgi membranes under conditions where ER-exit was inhibited. When the anterograde but not the retrograde membrane traffic between the ER and the Golgi is inhibited by caffeine, two things could happen to the Golgi membranes: all the Golgi membranes would recycle to the.....
Document: Since 10 mM caffeine at 20~ did not prevent the BFA-induced retrograde movement of Golgi membranes to the ER, it was of interest to study the distribution of the pre-Golgi and the Golgi membranes under conditions where ER-exit was inhibited. When the anterograde but not the retrograde membrane traffic between the ER and the Golgi is inhibited by caffeine, two things could happen to the Golgi membranes: all the Golgi membranes would recycle to the ER as in the case of BFA or part of the Golgi would do so.
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