Comparison of cytokine expression profiles in infants with a rhinovirus induced lower respiratory tract infection with or without wheezing: a comparison with respiratory syncytial virus

Roh, Da Eun; Park, Sook-Hyun; Choi, Hee Joung; Kim, Yeo Hyang

Of the T-helper 1-type cytokines, the concentration of IFN-γ was lower in the RV group compared to the RSV group, although it was not significantly different (10.29±9.25 pg/mL vs. 12.23±11.23 pg/ mL, P=0.474). In the RV group, the concentration of IFN-γ was higher in the patients with wheezing than in the patients without wheezing, and this finding was significantly different (14.88±9.24 pg/mL vs. 9.68±10.49 pg/mL, P=0.022) (Fig. 1 ). In the RSV group, the concentration of IFN-γ did not reach statistical significance between in the patients with wheezing and in the patients without wheezing (10.57±5.71 pg/mL vs. 15.19±7.96 pg/mL, P=0.105) (Fig. 1) . Especially, the concentration of IFN-γ was not significantly different between the RV group with wheezing and the RSV group with wheezing (14.88±9.24 pg/mL vs. 10.57±5.71 pg/mL, P=0.155) (Fig. 1 ), in contrast with significant difference between the RV group without wheezing and the RSV group without wheezing (9.68± 10.49 pg/mL vs. 15.19±7.96 pg/mL, P=0.019) (Fig. 1) .