Author: Hayward, Gail; Thompson, Matthew; Heneghan, Carl; Perera, Rafael; Del Mar, Chris; Glasziou, Paul
Title: Corticosteroids for pain relief in sore throat: systematic review and meta-analysis Document date: 2009_8_6
ID: 67bhdlzy_10
Snippet: We did sensitivity analyses, excluding each study in turn, to determine the stability of the effect. A priori subgroup analyses included age, route of corticosteroid, presence of positive bacterial culture or direct antigen test, and severity of sore throat including presence of exudate. Meta-regression in STATA tested subgroup interaction on the outcomes. We selected the data closest to a single-dose regimen from those studies that used differen.....
Document: We did sensitivity analyses, excluding each study in turn, to determine the stability of the effect. A priori subgroup analyses included age, route of corticosteroid, presence of positive bacterial culture or direct antigen test, and severity of sore throat including presence of exudate. Meta-regression in STATA tested subgroup interaction on the outcomes. We selected the data closest to a single-dose regimen from those studies that used different dosing regimens in a single trial as our conservative strategy. Similarly, if both oral and intramuscular data were available, we used oral data for our overall analysis and intramuscular data for appropriate subgroup analysis.
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