Author: SOMA, Takehisa; MATSUBAYASHI, Makoto; SASAI, Kazumi
Title: Detection of kobuvirus RNA in Japanese domestic dogs Document date: 2016_8_2
ID: 5b8i71jd_15
Snippet: The diarrheal pathogenicity of CaKoV in dogs has not been fully elucidated, and it is still not clear whether CaKoV is diarrheagenic. [2, 5, 17] . Based on results of the present study showing that viral RNA was detected in approximately half of the examined healthy kenneled dogs, we suggest that it may not be a primary pathogen in dogs. However, all of the diarrheal dogs were found not to be infected with CPV-2, the most important diarrheal path.....
Document: The diarrheal pathogenicity of CaKoV in dogs has not been fully elucidated, and it is still not clear whether CaKoV is diarrheagenic. [2, 5, 17] . Based on results of the present study showing that viral RNA was detected in approximately half of the examined healthy kenneled dogs, we suggest that it may not be a primary pathogen in dogs. However, all of the diarrheal dogs were found not to be infected with CPV-2, the most important diarrheal pathogen. Furthermore, 20.0% of the CaKoV-positive dogs were negative for other major diarrhea causative viruses, such as CDV, CAdV-1, CCoV and CRV. Recent epidemiological studies suggested possible involvement of porcine kobuvirus in diarrheal disease seen in piglets [3, 19] . Thus, it is possible that CaKoV might be involved in diarrheal disease seen in dogs as a mild or secondary infection factor, though various factors other than these viral infections can be related to an episode of diarrheal disease.
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