Selected article for: "cell adhesion and NK LM cell adhesion"
Title: Triggering through CD16 or phorbol esters enhances adhesion of NK cells to laminin via very late antigen 6
  • Document date: 1992_11_1
    • ID: 3ymo8zw0_30
    Snippet: Some of these mechanisms could explain how phosphorylation of a6, induced by CD16 engagement or TPA treatment, results in the enhancement of VLA-6-mediated NK cell adhesion to LM . The lack of correlation between a6 phosphorylation and enhanced adhesion, observed after 20 min of CD16 stimulation, suggests that phosphorylation-induced conformational changes last longer than cx6 phosphorylation, and that they are more likely responsible than phosph.....
    Document: Some of these mechanisms could explain how phosphorylation of a6, induced by CD16 engagement or TPA treatment, results in the enhancement of VLA-6-mediated NK cell adhesion to LM . The lack of correlation between a6 phosphorylation and enhanced adhesion, observed after 20 min of CD16 stimulation, suggests that phosphorylation-induced conformational changes last longer than cx6 phosphorylation, and that they are more likely responsible than phosphorylation per se for the high avidity state of the receptor.

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