Author: Mayla Borba; Fernando de Almeida Val; Vanderson Sousa Sampaio; Marcia Araujo Alexandre; Gisely Cardoso Melo; Marcelo Brito; Maria Mourao; Jose Diego Brito Sousa; djane Baia-da-Silva; Marcus Vinitius Farias Guerra; Ludhmila Hajjar; Rosemary Costa Pinto; Antonio Balieiro; Felipe Gomes Naveca; Mariana Xavier; Alexandre Salomao; Andre Siqueira; Alexandre Schwarzbolt; Julio Henrique Rosa Croda; Mauricio Lacerda Nogueira; Gustavo Romero; Quique Bassat; Cor Jesus Fontes; Bernardino Albuquerque; Claudio Daniel-Ribeiro; Wuelton Monteiro; Marcus Lacerda
Title: Chloroquine diphosphate in two different dosages as adjunctive therapy of hospitalized patients with severe respiratory syndrome in the context of coronavirus (SARS-CoV-2) infection: Preliminary safety results of a randomized, double-blinded, phase IIb clinical trial (CloroCovid-19 Study) Document date: 2020_4_11
ID: ifxm3j4y_16
Snippet: Coronaviruses, first discovered in the 1960s, are a family of RNA viruses that typically cause respiratory and intestinal infections in birds and mammals. In humans, coronaviruses often cause mild upper respiratory tract infections, and together with rhinoviruses are the two main underlying aetiologies for the normal cold, with severe disease secondary to these viruses usually restricted to immunocompromised individuals 1 formerly 2019-nCoV), was.....
Document: Coronaviruses, first discovered in the 1960s, are a family of RNA viruses that typically cause respiratory and intestinal infections in birds and mammals. In humans, coronaviruses often cause mild upper respiratory tract infections, and together with rhinoviruses are the two main underlying aetiologies for the normal cold, with severe disease secondary to these viruses usually restricted to immunocompromised individuals 1 formerly 2019-nCoV), was confined to the Hubei province, but it rapidly spread to many other countries 8, 9 , compelling WHO to officially declare a global pandemic on March 11, 2020. The origin of the virus has yet to be fully elucidated, but genomic analysis suggests that it is closely related to viruses previously identified in bats 10 .
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