Author: Baumeier, Christian; Schlüter, Luisa; Saussenthaler, Sophie; Laeger, Thomas; Rödiger, Maria; Alaze, Stella Amelie; Fritsche, Louise; Häring, Hans-Ulrich; Stefan, Norbert; Fritsche, Andreas; Schwenk, Robert Wolfgang; Schürmann, Annette
Title: Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease Document date: 2017_8_4
ID: 64az0pco_29_2
Snippet: mmatory actions by upregulating toll-like receptors (TLRs) in kidney and adipose tissue, while DPP4 inhibition has anti-inflammatory effects [48] . The present data demonstrate an increased expression of macrophage markers and proinflammatory cytokines in adipose tissue of Dpp4-Liv-Tg mice, despite no effects on adipose Dpp4 expression......
Document: mmatory actions by upregulating toll-like receptors (TLRs) in kidney and adipose tissue, while DPP4 inhibition has anti-inflammatory effects [48] . The present data demonstrate an increased expression of macrophage markers and proinflammatory cytokines in adipose tissue of Dpp4-Liv-Tg mice, despite no effects on adipose Dpp4 expression.
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