Author: TAKANO, Tomomi; YAMASHITA, Saya; MURATA-OHKUBO, Michiko; SATOH, Kumi; DOKI, Tomoyoshi; HOHDATSU, Tsutomu
Title: Prevalence of canine coronavirus (CCoV) in dog in Japan: detection of CCoV RNA and retrospective serological analysis Document date: 2015_10_11
ID: 2kg967bh_14
Snippet: Generally, CCoV-infection has been recognized as an infectious disease causing mild diarrhea, but severe systemic disease characterized by hemorrhagic gastroenteritis and leukopenia in CCoV-II-infected dogs have recently been reported [2, 9] . At present, such serious symptoms in CCoV-I-infected dogs have not been reported, but it has been clarified that: i) coronaviral genomes readily mutate in hosts and ii) genomic recombination with another co.....
Document: Generally, CCoV-infection has been recognized as an infectious disease causing mild diarrhea, but severe systemic disease characterized by hemorrhagic gastroenteritis and leukopenia in CCoV-II-infected dogs have recently been reported [2, 9] . At present, such serious symptoms in CCoV-I-infected dogs have not been reported, but it has been clarified that: i) coronaviral genomes readily mutate in hosts and ii) genomic recombination with another coronavirus causes large-scale mutation of coronavirus [5, 17] . On the basis of these facts, CCoV-I may acquire the pathogenicity of CCoV-II and become the novel virulent CCoV-I.
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