Selected article for: "comparative genomic analysis and genomic analysis"

Author: Pickett, Brett E.; Sadat, Eva L.; Zhang, Yun; Noronha, Jyothi M.; Squires, R. Burke; Hunt, Victoria; Liu, Mengya; Kumar, Sanjeev; Zaremba, Sam; Gu, Zhiping; Zhou, Liwei; Larson, Christopher N.; Dietrich, Jonathan; Klem, Edward B.; Scheuermann, Richard H.
Title: ViPR: an open bioinformatics database and analysis resource for virology research
  • Document date: 2011_10_17
  • ID: 48ym7eti_1
    Snippet: Viral disease outbreaks tend to occur every several years in the human population (1) (2) (3) (4) . During such outbreaks, identification of the causative agent and comparative genomic analysis can be critical to limiting the spread of the virus and identifying suitable treatment options. While the first lines of defense against such outbreaks are clinical reporting and automated surveillance, 'wet lab' experimentation of viral isolates is also i.....
    Document: Viral disease outbreaks tend to occur every several years in the human population (1) (2) (3) (4) . During such outbreaks, identification of the causative agent and comparative genomic analysis can be critical to limiting the spread of the virus and identifying suitable treatment options. While the first lines of defense against such outbreaks are clinical reporting and automated surveillance, 'wet lab' experimentation of viral isolates is also important. Bioinformatics tools and database resources that provide information about the genomic structures and phenotypic characteristics of known viruses can make this process more efficient by supporting data mining for the development of hypotheses worthy of in-depth laboratory experimentation on the emerging strain.

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