ViPR: an open bioinformatics database and analysis resource for virology research

Pickett, Brett E.; Sadat, Eva L.; Zhang, Yun; Noronha, Jyothi M.; Squires, R. Burke; Hunt, Victoria; Liu, Mengya; Kumar, Sanjeev; Zaremba, Sam; Gu, Zhiping; Zhou, Liwei; Larson, Christopher N.; Dietrich, Jonathan; Klem, Edward B.; Scheuermann, Richard H.

Data from public archives. The ViPR database integrates various types of data acquired from multiple publicly accessible database resources (Supplementary Table S1 ). Specifically, ViPR includes >64 000 genomic segment sequences from GenBank (9), >220 000 protein sequences from UniProt (10), >1400 experimentally determined T-cell and B-cell epitopes from the Immune Epitope Database (IEDB; www.iedb.org) (11), >2900 structures from the Protein Data Bank (PDB; www.pdb.org) (12) and >59 000 Gene Ontology annotations (GO, www. geneontology.org) (13) (Supplementary Table S2 ). All these data are updated with each bimonthly release and are directly searchable using intuitive web-based user interfaces.